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A small 2018 pilot study on 24 participants using 0.05% AHK-Cu serum twice daily for 12 weeks found statistically significant improvements in fine line depth (measured via profilometry) and skin elasticity (measured via cutometry) compared to placebo

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Nevertheless, the medicine is correlated with diminished all-cause mortality in patients undergoing colchicine therapy, and its administration has been associated with a lowered risk of acute coronary syndrome in individuals with confirmed coronary artery disease (Martínez et al., 2015[61])